DNA methylation-based sex classifier to predict sex and identify sex chromosome aneuploidy

Sex Chromosome Aneuploidy: Prospective Studies on Children

This two-volume publication contains the proceedings of a NATO Advanced Study Institute, held in April 1978. The material is organized in five sections. In the first section J. Bonner presents a historic review of chromatin research. The following section describes biophysical and chemical methods used in the study of isolated chromatin, such as electron microscopy, circular dichroism, X-ray di...

Karyotype and Sex-Chromosome Polymorphism in Nesokia indica, from Iran

Targeted cell‐free DNA analysis with microarray quantitation for assessment of fetal sex and sex chromosome aneuploidy risk

The accuracy of targeted cell-free DNA (cfDNA) testing with DANSRTM and FORTETM for trisomies 21, 18 and 13 has been well demonstrated and is consistent across next generation sequencing and microarray quantitation methods1. Targeted cfDNA analysis for fetal sex chromosome aneuploidy (SCA) has also been validated and shown to have high specificity in prospective studies2,3. This study expands u...

Children with Sex Chromosome Aneuploidy: Follow-Up Studies

The third chapter reviews the pharmacologic properties of antiplatelet drugs and the antiplatelet effects of drugs used in general medical practice. The drugs discussed include aspirin, non-steroidal anti-inflammatory agents, sulfinpyrazone, prostaglandins PGE1 and PGI2, dipyridamole, and other pyridamole-pyrimidine compounds. Especially helpful is a section on the effects of anesthetics, major...

Molecular diagnosis of sex chromosome aneuploidy using quantitative PCR.

Numeric sex chromosome imbalances, or aneuploidies, are present in several pathological conditions including tumors, abnormal gestations, and clinical syndromes. Here we report a method to identify karyotypic imbalances of the X and Y chromosomes using the polymerase chain reaction (PCR). The polymerase chain reaction was used to quantitatively coamplify the sex chromosome linked genes ZFX and ...